DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

In an effort to facilitate collaborations and speed GWI research, the GWIRP has compiled a list of various research resources produced from our funding. The list displays available resources and contact information. Please contact the PI(s) directly for information and requests.

Biomarkers
Award Number PI Product(s) References Contact Information

GW080080

Ronald Bach

CRP-Associated Plasma Biomarkers of Inflammation

Johnson GJ, Leis LA, Slater BCS, et al. 2013. Elevated platelet count, CRP and thromboxane analog-induced platelet aggregation in subjects with Gulf War Veterans' Illnesses: Evidence of a chronic inflammatory state? Blood Coagul Fibrinolysis 24(7):736-741.

Johnson GJ, Slater BCS, Leis LA et al. 2016. Blood Biomarkers of Chronic Inflammation in Gulf War Illness. PLoS ONE 11(6): e0157855.doi:10.1371/journal.pone.0157855

ronald.bach@va.gov

GW080053

James Baraniuk

Cardiovascular indices and imaging based biomarkers post exercise challenge

Rayhan RU, Stevens BW, Raksit MP,et al. 2013. Exercise challenge in Gulf War Illness reveals two subgroups with altered brain structure and function. PLoS One 8(6):e63903

baraniuj@georgetown.edu

GW080152

Nancy Klimas, Gordon Broderick

Altered immune pathway activity

Broderick G, Ben-Hamo R, Vashishtha S, et al. 2013. Altered immune pathway activity under exercise challenge in Gulf War Illness: An exploratory analysis. Brain, Behavior, and Immunity 28 (2013) 159 — 169

nklimas@nova.edu

gbroderick@nova.edu

GW110044

Jarred Younger

Immune factors to predict daily symptom severity in GWI

Parkitny L, Middleton S, Baker K, et al. 2015. Evidence for abnormal cytokine expression in Gulf War Illness:

A preliminary analysis of daily immune monitoring data. BMC immunology 16(1):57.

younger@uab.edu

GW120033

Lisa Pierce

miRNA and epigenetic biomarkers

Pierce LM, Kurata WE, Matsumoto KW, Clark ME, and Farmer DM. 2016. Long-term epigenetic alterations in a rat model of Gulf War Illness. Neurotoxicology 55:20-32.

lisa.m.pierce.civ@mail.mil

GW120071

Beatrice Golomb

Alterations in mitochondrial function (prolonged PCr-recovery time constant)

Koslik HJ, Hamilton G, and Golomb BA. 2014. Mitochondrial dysfunction in Gulf War illness revealed by 31Phosphorus Magnetic Resonance Spectroscopy: a case-control study. PLoS One 9(3):e92887.

bgolomb@ucsd.edu

GW100076

GW130045

Ghania Ait-Ghezala Laila Abdullah

lysophospholipid species (lysophophatidylcholine and lysophosphatidylethanolamine)

Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE, et al. (2017). Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness. PLoS ONE 12(4): e0176634.

gaitghezala@roskampinstitute.net

labdullah@roskampinstitute.net

Last updated Monday, October 16, 2017