Research Resources Initiative by the NFRP

The NFRP now offers a service on our website featuring a listing of available NF research resources! Our goal is to facilitate and speed NF research by publicizing new resources and aiding collaborations. The list displays available resources and repository or PI contact information. Please contact the repository or PI directly for information and requests.

Cell and Molecular Bio Tools
Award Number	PI	Product or Resource	References	Contact Information or Link
NF100160	Toshifumi Tomoda	Plasmids for the autophagy-related protein Unc51.Atg1-myc and the NF2 point mutation Merlin K79E-myc		ttomoda@coh.org
NF093079	Pamela Vanderzalm	Kinase domains of Hpo (aa. 1-367), MST1 (aa 1-320), and MST2(aa 1-316) in pGEX expression vector	Boggiano JC, et al. 2011. Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Developmental Cell 21(5):888-895.	Dr. Richard Fehon rfehon@uchicago.edu
NF093039	Jonathan Chernoff	NF1 gene repair vector designed to replace the disrupted Nf1 allele in a mouse model by restoring exon 31.		Jonathan.Chernoff@fccc.edu
NF080062	Lawrence Kirschner	pcDNA3.1 encoding wildtype Rac1, Rac1 Q61L, or Rac1 T17N		Lawrence.Kirschner@osumc.edu
NF030070	Long-Sheng Chang	pUASP myc-tagged merlin constructs: Mer+ (wild type) Mer3 mutant (Met177Ile) MerΔBB mutant (Blue Box deletion) Mer1-379 mutant Mer^345-635 mutant	Dorogova NV, et al. 2008. The role of Drosophila Merlin in spermatogenesis. BMC Cell Biology Jan 10;9:1. Yudina OS, et al. 2010. The role of the functional sites of the merlin tumor suppressor in Drosophila spermatogenesis. Russian Journal of Genetics 46(10):1214-1216.	lchang@chi.osu.edu
NF073146	Susan Lindquist	pBabe vector encoding EGFP and pBabe vector encoding dominant-negative MEK1 mutant (Ser218Ala and Ser222Ala)	Dai C, Santagata S, Tang Z, et al. 2012. Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. J Clin Invest 122(10):3742-3754.	lindquist_admin@wi.mit.edu