DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

The NFRP now offers a service on our website featuring a listing of available NF research resources!! Our goal is to facilitate and speed NF research by publicizing new resources and aiding collaborations. The list displays available resources and repository or PI contact information. Please contact the repository or PI directly for information and requests.

Award Number PI Product or Resource References Contact Information or Link
Drosophila Models

NF080075
NF073069

James Walker and
Andre Bernards

Snr101319 homozygous Drosophila expressing:

  1. actin5C-GAL4>SMARCB1-a
  2. actin5C-GAL4>SMARCB1-B
  3. actin5C-GAL4>SMARCB1 P14H
  4. actin5C-Gal4>SMARCB1 R53L
  5. actin5C-GAL4>SMARCB1 ΔExon 4

 

jwalker@helix.mgh.harvard.edu

NF080012

Michael Stern

  1. D42>CaMKIIT287D
  2. D42>CaMKIIT287A
  3. D42>ala
  4. DFaKCG1,D42>DFaK+
  5. DFaKCG1, D42>CaMKIIT287D
  6. D42>PI3KDN, CaMKIIT287D
  7. D42>PI3K-CAAX, ala
  8. DFaKCG1,D42>PI3K-CAAX
  9. DmGluRA112b;D42>CaMKIIT287D
  10. DmGluRA112b; D42>+

Lin C et al. 2011. The metabotropic glutamate receptor activates the lipid kinase PI3K in Drosophila motor neurons through calcium/calmodulin-dependent protein kinase II and the nonreceptor tyrosine kinase DFaK. Genetics 188:601-613.

stern@rice.edu

NF030006

Michael Stern

  1. D42>PI3K-CAAX
  2. DmGluRA112b;D42>PI3K-CAAX
  3. D42>PI3KDN
  4. Foxo21/Foxo25
  5. Foxo21/Foxo25;OK6>PI3KDN
  6. D42>PI3K-CAAX;Foxo+
  7. OK6>PI3KDN
  8. D42>Foxo+
  9. D42>PI3K-CAAX;S6KDN
  10. D42>S6KACT
  11. D42>S6KDN
  12. gli>RasV12
  13. PI3K2H1;gli>RasV12
  14. gli>PI3KDN,RasV12
  15. gli>PI3K-CAAX
  16. PI3K2H1/PI3KA;gli>PI3K-CAAX
  17. MZ709>PI3K-CAAX
  18. gli-RafF179
  19. gli>RalV20
  20. Akt4226;gli>PI3K-CAAX
  21. Akt4226/+;gli>PI3K-CAAX
  22. gli>PI3K-CAAX;Foxo+(f19-5)
  23. gli>PI3K-CAAX, Foxo+(m3-1)
  24. gli>PI3K-CAAX, GFP

Howlett E, et al. 2008. A PI3-kinase-mediated negative feedback regulates neuronal excitability. Public Library of Science Genetics 4 e1000277.

Lavery W, et al. 2007. Phosphatidyl inositol 3-kinase and Akt nonautonomously promote perineural glial growth in Drosophila peripheral nerves. Journal of Neuroscience27:279-288.

stern@rice.edu