Since Fiscal Year 2009, the Peer Reviewed Cancer Research Program (PRCRP) has been charged by U.S. Congress to fund innovative basic, applied, and translational cancer research to support Service members, their families, and the American public. Members of the military are exposed to hazardous environments due to the nature of their service and deployments and, thus, are at risk for the development of many types of cancers. The mission of the PRCRP is to successfully promote high impact research. To accomplish this task, the PRCRP seeks to fund different areas of the research landscape. Funding innovative and translational research the PRCRP offers funding opportunities directed toward the special focus of Service members and potential cancer risks; focusing on the gaps in cancer research with respect to unique situations and military environments. Additionally, the PRCRP addresses growing and developing the future in research through targeted funding opportunities for early career investigators. With a funding program focused on military health and welfare in cancer research, the PRCRP strives to improve the quality of life by decreasing the impact of cancer on Service members, their families and the American public by funding highly relevant and innovative research.