DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

NEWS RELEASE

Released: February 13, 2008

Department of Defense Peer Reviewed Medical Research Program
Funding Opportunities for Fiscal Year 2008

The Fiscal Year 2008 (FY08) Defense Appropriations Act provides $50 million to the Department of Defense Peer Reviewed Medical Research Program (PRMRP) to support the best medical research to protect and support military personnel and their beneficiaries and to eradicate diseases that impact these populations. This program is administered by the US Army Medical Research and Materiel Command through the Office of the Congressionally Directed Medical Research Programs (CDMRP).

FY08 PRMRP Supplements to the Broad Agency Announcement (BAA) will be released by April 2008 for the award mechanisms listed in the table below. Proposed research must be focused in one of the following 21 Congressionally directed topic areas: Alcoholism Research, Amyotrophic Lateral Sclerosis, Blood Cancer, Drug Abuse, Epilepsy Research, Eye and Vision Research, Integrated Tissue Hypoxia Research, Interstitial Cystitis, Inflammatory Bowel Disease, Leishmaniasis, Lupus, Kidney Cancer, Mesothelioma, Multiple Sclerosis, Nutrition and Health Promotion, Paget's Disease, Polycystic Kidney Disease, Pulmonary Hypertension, Scleroderma, Social Work Research, Tinnitus.

Award Mechanism

Eligibility

Key Mechanism Elements

Funding

Investigator-Initiated Research Award

Independent Investigators

  • To support military-relevant health-related basic research that will make an original and important contribution to the field (topic area) of interest
  • Strategic research is encouraged
  • Clinical trials will not be funded

  • A maximum of $900,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
  • Anticipate 16 awards

Translational Research Award

Independent Investigators and/or practicing clinicians

  • To support translational research focused on a military-relevant health-related central problem or question from a bench-to-bedside-to-bench perspective that has the potential to make a strong impact on the field (topic area) of interest
  • Strategic research is encouraged
  • Investigation of new combinations of standard therapies will not be funded
  • Clinical trials will not be funded

  • A maximum of $900,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
  • Anticipate 6 awards

Advanced Technology/ Therapeutic Development Award

Independent Investigators

  • To support military-relevant health-related development of new therapies, diagnostics, or clinical policy/guidance that has the potential to make a strong impact on the field (topic area) of interest
  • Product-oriented
    • Device
    • Drug
    • Clinical policy/guidance
  • Clinical trials will not be funded

  • A maximum of $2.0 million for direct costs for up to a 4-year performance period, plus indirect costs as appropriate
  • Anticipate 2 awards

Clinical Trial Award

Independent Investigators

  • To support rapid implementation of military-relevant health-related clinical trials of novel interventions with the potential to have a significant impact
  • IND* or IDE↑ applications should be in process/completed before proposal submission
  • Clinical trial is expected to be initiated within 6 months of award date

  • A maximum of $2.5 million for direct costs for up to a 4-year performance period, plus indirect costs as appropriate
  • Anticipate 2 awards
*Investigational New Drug
↑Investigational Device Exemption

Information in this preannouncement is being provided to allow investigators time to plan and develop proposals. All proposals submitted must conform to the requirements specified in the final Supplements to the BAA, to be posted in Grants.gov by April 2008. The number of awards anticipated is based on available funds and average cost of proposals. The PRMRP reserves the right to make awards in greater or lesser numbers than anticipated. As of 2007, proposals requesting funding from the CDMRP have been submitted through the Federal Government's single entry portal, Grants.gov, in compliance with Public Law 106-107. Each Supplement to the BAA and Application Instructions, which detail the pre-application and proposal submission process, along with the required forms for proposal submission, will be available electronically for downloading from the Grants.gov website (http://www.grants.gov) upon release. Each award mechanism will require submission of a pre-application including a letter of intent (LOI) through the CDMRP eReceipt website, https://cdmrp.org. Supplements to the BAA will also be available on the CDMRP website (http://cdmrp.army.mil). Pre-application LOI and proposal submission deadlines will be listed in the Supplements to the BAA.

Requests for email notification of the Supplement to the BAA release may be sent to Help@cdmrp.org. For more information about the PRMRP or other CDMRP-sponsored programs, please visit the CDMRP website.

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