IMPORTANT: All applications for FY10 PCRP funding must address at least one of the FY10 PCRP Overarching
Challenges and at least one of the six PCRP Focus Areas:
- Overarching Challenges: Development of effective treatments for advanced disease, Distinguishing lethal
from indolent disease
- Focus Areas: Imaging, Biomarkers, Therapy, Genetics, Tumor Biology, Survivorship
|
| Award Mechanism |
Eligibility |
Key Mechanism Elements |
Funding |
| Exploration-Hypothesis Development Award |
Investigators at all academic levels (or equivalent) |
- Supports highly innovative, untested, potentially groundbreaking concepts in prostate cancer
- Emphasis is on Innovation; potential impact may be unknown
- Human studies investigation is permitted provided it is exempt
- Preliminary data are not allowed
|
- Maximum funding of $75K for direct costs (plus indirect costs)
- Period of performance cannot exceed 18 months
|
| Health Disparity Research Award |
Independent investigators at or above the level of Assistant Professor (or equivalent); OR
NEW for FY10!
New Investigator Option: PIs must meet the following criteria at the application submission deadline:
- Must be an independent investigator (have the freedom to pursue individual aims without formal mentorship), AND
- Have not previously received a PCRP New Investigator Award, AND
- Either have completed at least 3 years of postdoctoral training or fellowship OR are within 5 years of having received
first independent faculty position (or equivalent)
|
- Supports new ideas that represent innovative, high-risk/high-gain approaches to prostate cancer health
disparity research that have the potential to make an important contribution to eliminating death and
suffering from prostate cancer
- PI(s) and/or collaborator(s) should have a connection to, or effectiveness in working with, an affected population or community
- Preliminary data are encouraged but not required
- Emphasis is on Innovation and Impact
- Clinical trials are not allowed
|
- Maximum funding of $450K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Health Disparity Training Award |
Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Must be enrolled full-time in an accredited doctoral program and must have completed all predissertation
requirements by October 1, 2010
Postdoctoral Ph.D. PIs:
- Must have successfully defended a doctoral thesis by October 1, 2010; and
- Have 3 years or less of postdoctoral fellowship experience by October 1, 2010
Postdoctoral M.D. PIs:
- Must have an M.D.; AND
- Must be able to devote at least 40% effort; AND
- By August 1, 2010, must be:
- Enrolled in an accredited intern training program, OR
- Enrolled in an accredited residency or fellowship program with at least 2 years of training remaining,
OR
- Within 3 years of the last formal training
|
- Supports training in prostate cancer health disparity research for individuals in the early stages of their careers
- PIs must have a designated mentor who is an experienced prostate cancer health disparity researcher
- PI or mentor must demonstrate a connection to, or effectiveness in working with, the affected population or community
- Emphasis is on PI, Mentor, and Training Program and Environment
|
Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Maximum funding of $92.5K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 3 years
Postdoctoral M.D. or Ph.D. PIs:
- Maximum of $115K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 2 years
|
| Idea Development Award |
NEW for FY10!
New Investigator Option: Principal Investigators (PIs) must meet the following criteria at the application
submission deadline:
- Must be an independent investigator (have the freedom to pursue individual aims without formal
mentorship), AND
- Have not previously received a PCRP New Investigator Award, AND
- Either have completed at least 3 years of postdoctoral training or fellowship OR are within 5 years of
having received first independent faculty position (or equivalent)
|
- Preproposal is required; application submission is by invitation only
- Supports new ideas that represent innovative, high-risk/high-gain approaches to prostate cancer research,
and have the potential to make an important contribution to eliminating death and suffering from prostate
cancer
- Preliminary data are encouraged but not required
- Emphasis is on Innovation and Impact
- Clinical trials are not allowed
- New Investigator Option supports applicants early in their faculty appointments or in the process of
developing independent research careers
|
- Maximum funding of $450K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Impact Award (NEW!) |
Independent investigators at or above the level of Assistant Professor (or equivalent) |
- Preproposal is required; application submission is by invitation only
- Supports high-impact studies towards reducing or eliminating the problem of overtreatment of primary
prostate cancer
- Areas of special interest include but are not limited to active surveillance, biomarkers, improved
staging, local staging, and optimal measures for follow-up and biopsy
- Multidisciplinary teams inclusive of strong clinical expertise are a key feature
- Preliminary data to support feasibility are required
- Emphasis is on the Research Question and Impact
- Allows clinical trials
|
- Maximum funding of $750K for direct cost (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Laboratory- Clinical Transition Award |
Investigators at all academic levels (or equivalent) |
- Supports goal- and product-driven preclinical studies of promising lead agents or targets that may
revolutionize prostate cancer clinical care
- PIs are expected to have identified and have access to either one lead agent or a limited number of lead
agents for optimization, or a validated target before applying
- Preliminary data are required to demonstrate validated target availability or lead agent(s) in human
prostate cancer
- Does not support target discovery, drug screening, device development, development of diagnostic
biomarkers, studies of conventional therapeutics, or clinical trials
- Emphasis is on Lead Agent, Research Strategy, and Clinical Impact
|
- Maximum funding of $750K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Physician Research Training Award |
At the time of proposal submission, the PI must be either:
- A physician with clinical duties and/or responsibilities in the last year of an accredited medical
residency or medical fellowship program; or
- A physician within 3 years of first independent faculty appointment
|
- Supports training of physicians with clinical duties for careers in prostate cancer research
- PIs must have a designated mentor with an established research program in prostate cancer
- Institutions must provide at least 40% protection of PI's time for research
- Emphasis is on PI, Mentor, and Training Program and Environment
|
- Maximum funding of $130K per year for direct costs (plus 8% indirect costs)
- Period of performance is 3 years minimum to 5 years maximum
|
| Population-Based Research Award |
Independent investigators at or above the level of Assistant Professor (or equivalent) |
- Supports high-impact approaches to prostate cancer research from the perspective of population-based
studies that will, if successful, significantly accelerate the elimination of death and suffering from
prostate cancer
- Population-based studies may include case-control, retrospective, prospective, and cohort studies
provided that the study population is of sufficient size to provide appropriate statistical power
- Topics may include but are not limited to epidemiology, molecular genetics, germline and somatic
genomics, risk prediction, disease aggressiveness, predictors of therapeutic response and progression, and
health disparity
- Requires a robust statistical plan and strong biostatistical expertise in the study team
- Emphasis is on Impact and Research Strategy and Feasibility
- Clinical trials are not allowed
|
- Maximum funding of $600K for direct costs (plus indirect costs)
- Period of performance cannot exceed 4 years
|
| Prostate Cancer Training Award |
Postdoctoral Ph.D. PIs:
- Must be enrolled full-time in an accredited doctoral program and must have completed all predissertation
requirements by October 1, 2010
Must have successfully defended a doctoral thesis by October 1, 2010; and
- Must have successfully defended a doctoral thesis by October 1, 2010; and
- Have 3 years or less of postdoctoral fellowship experience by October 1, 2010
Postdoctoral M.D. PIs:
- Must have an M.D.; AND
- Must be able to devote at least 40% effort; AND
- By August 1, 2010, must be:
- Enrolled in an accredited intern training program, OR
- Enrolled in an accredited residency or fellowship program with at least 2 years of training
remaining, OR
- Within 3 years of the last formal training
|
- Supports prostate cancer research training for individuals in the early stages of their careers
- PIs must have a designated mentor
- Emphasis is on PI, Mentor, and Training Program and Environment
|
- Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Maximum funding of $92.5K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 3 years
- Postdoctoral M.D. or Ph.D. PIs:
- Maximum of $115K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 2 years
|
| Synergistic Idea Development Award |
Two or three independent investigators at or above the level of Assistant Professor (or equivalent) |
- Preproposal is required; application submission is by invitation only
- Supports new or existing partnerships between two or three independent investigators to address a
central innovative question in prostate cancer that may include high risk, provided there is a potential for
significant impact
- Preliminary data are encouraged but not required
- Emphasis is on Synergy, Innovation, and Impact
- Clinical trials are not allowed
|
- Maximum funding of $750K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
The government reserves the right to make changes to the award mechanisms offered and the mechanism elements if
necessary. All applications must conform to the final Program Announcements and application instructions that will
be available for electronic downloading from the Grants.gov website. The application package containing the
required forms for each award mechanism will also be found on Grants.gov. A listing of all USAMRMC funding
opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
A pre-application is required for all award mechanisms and must be submitted through the CDMRP eReceipt website
(http://cdmrp.org) prior to application submission. Applications must be submitted
through the federal government's single-entry portal, Grants.gov. Requests for
email notification of the program announcements release may be sent to help@cdmrp.org.
For more information about the PCRP or other CDMRP-administered programs, please visit the CDMRP website
(http://cdmrp.army.mil).
Requests for email notification of the release of program announcements may be sent to
Help@cdmrp.org. For more information about the PCRRP or other CDMRP-sponsored programs, please visit the CDMRP
website (http://cdmrp.army.mil).
Point of Contact:
