New Research Resources Initiative by the TSCRP
The TSCRP now offers a service on our website featuring a listing of newly available TSC research resources!! Our goal is to facilitate and speed TSC research by publicizing new resources and aiding collaborations. The list displays available resources and PI contact information. Please contact the PIs directly for information and requests.
| Award Number | PI | Product or Resource | References | Contact Information or Link |
| Mouse Models | ||||
|---|---|---|---|---|
|
Boyi Gan |
Rosa26CreERT2, FoxO1/3/4 L/L, TSC1 L/+ mice |
Gan B, et al. 2010. FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell 18:472-484. |
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|
Angelique Bordey |
Model of tuber-like lesions: Tsc1fl/mut |
Feliciano DM, et al. 2011. Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice. Journal of Clinical Investigation 121(4):1596-1607. |
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|
Michael Gambello |
Loss of Tsc2 in Purkinje cells:
|
Reith RM, et al. 2011. Loss of the tuberous sclerosis complex protein tuberin causes Purkinje cell degeneration. Neurobiology of Disease 43(1):113-122. |
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|
Bo Xiao |
Rosa26-Rheb1 S16H and Rosa26-Rheb1 wild type mice |
Zou J, et al. 2011. Rheb1 is required for mTORC1 and myelination in postnatal brain development. Developmental Cell 20(1):97-108. |
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|
Kiran Chada |
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