DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

The NFRP now offers a service on our website featuring a listing of available NF research resources!! Our goal is to facilitate and speed NF research by publicizing new resources and aiding collaborations. The list displays available resources and repository or PI contact information. Please contact the repository or PI directly for information and requests.

Award Number PI Product or Resource References Contact Information or Link
Antibodies

NF043043

Wallace Ip

Monoclonal and polyclonal antibodies against merlin and PPM1B.

Lepont et al. Point mutation in the NF2 gene of HEI-193 schwannoma cells results in expression of a non-growth suppressive merlin isoform. Mutation Research. 2008 Jan 1; 637(1-2); 142-151.

Robert.hennigan@cchmc.org

NF030020

David Gutmann

polyclonal rabbit anti-protein 4.1B

Robb VA, Gerber MA, Hart-Mahon EK, Gutmann DH: Membrane localization of the U2domain of Protein 4.1B is necessary and sufficient for meningioma growth suppression. Oncogene 24:1946-57, 2005.

Kuns R, Kissil JL, Newsham IF, Jacks T, Gutmann DH, Sherman LS: Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation. Oncogene 24:6502-15, 2005.

gutmannd@neuro.wustl.edu

NF010016

Marco Giovannini and David Gutmann

Polyclonal rabbit anti-TSLC1 and polyclonal rabbit anti-protein 4.1B

Surace E, et al. 2004. Loss of tumor suppressor in lung cancer-1 (TSLC1) expression in meningioma correlates with increased malignancy grade and reduced patient survival. Journal of Neuropathology and Experimental Neurology 63(10):1015-1027.

Mcclatchey AI and Giovannini M. 2005. Membrane organization and tumorigenesis-the NF2 tumor suppressor, Merlin. Genes Dev 19(19):2265-2277

gutmannd@neuro.wustl.edu

NF960027

Margaret Wallace

Polyclonal rabbit anti-neurofibromin: PcNFn27 Monoclonal rabbit anti-neurofibromin: McNFn27a and McNFn27b

Muir D, Neubauer D, Lim IT, Yachinis AT, Wallace MR. Tumorigenic Properties of Neurofibromin-Deficient Neurofibroma Schwann Cells. Am J Pathol. 2001 February; 158(2): 501-513.

http://www.pierce-antibodies.com (external link)
http://www.scbt.com (external link)