Neurofibromatosis
Research Resources Initiative by the NFRP
The NFRP now offers a service on our website featuring a listing of available NF research resources! Our goal is to facilitate and speed NF research by publicizing new resources and aiding collaborations. The list displays available resources and repository or PI contact information. Please contact the repository or PI directly for information and requests.
| Award Number | PI | Product or Resource | References | Contact Information or Link |
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Toshifumi Tomoda |
Plasmids for the autophagy-related protein Unc51.Atg1-myc and the NF2 point mutation Merlin K79E-myc |
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Pamela Vanderzalm |
Kinase domains of Hpo (aa. 1-367), MST1 (aa 1-320), and MST2(aa 1-316) in pGEX expression vector |
Boggiano JC, et al. 2011. Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Developmental Cell 21(5):888-895. |
Dr. Richard Fehon |
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Jonathan Chernoff |
NF1 gene repair vector designed to replace the disrupted Nf1 allele in a mouse model by restoring exon 31. |
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Lawrence Kirschner |
pcDNA3.1 encoding wildtype Rac1, Rac1 Q61L, or Rac1 T17N |
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Susan Lindquist |
pBabe vector encoding EGFP and pBabe vector encoding dominant-negative MEK1 mutant (Ser218Ala and Ser222Ala) |
Dai C, et al. 2012. Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. J Clin Invest 122(10):3742-3754. |
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Long-Sheng Chang |
pUASP myc-tagged merlin constructs:
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Dorogova NV, et al. 2008. The role of Drosophila Merlin in spermatogenesis. BMC Cell Biology Jan 10;9:1. Yudina OS, et al. 2010. The role of the functional sites of the merlin tumor suppressor in Drosophila spermatogenesis. Russian Journal of Genetics 46(10):1214-1216. |
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