The NFRP now offers a service on our website featuring a listing of available NF research resources! Our goal is to facilitate and speed NF research by publicizing new resources and aiding collaborations. The list displays available resources and repository or PI contact information. Please contact the repository or PI directly for information and requests.

Award Number PI Product or Resource References Contact Information or Link


Fernando Camargo

TEAD-based cell lines and screening technique


Jonathan Chernoff

Nf1 retargeting vector to repair NF1 allele in pluripotent stem cells


David Gutmann

PET technique to detect and evaluating promising agents for attention deficit in Nf1 mutant mice

Brown JA, et al. 2011. PET imaging for attention deficit preclinical drug testing in neurofibromatosis-1 mice. Exp Neurol 232(2):333-338


Steven Carroll

Orthotopic xenografting method for luciferase-tagged MPNST cells

Turk AN, et al. 2011. Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents. Journal of Visualized Experiments 49.

Byer SJ, et al. 2011. Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner. Neuro Oncol 13(1):28-41.


Andrew Hoffman

Associated chromosome trap (ACT) assay

Ling J and Hoffman AR. 2011. Associated chromosome trap for identifying long-range DNA interactions. J Vis Exp 23(50).


Norbert Perrimon

Technique to quantify phenotypic cell profiles facilitating screening for modifiers of NF1 and NF2 phenotypes.

Bakal C, Aach J, Church G, et al. 2007. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science 316(5832): 1753-1756

Nir O, Bakal C, Perrimon N, Berger B. (2010) Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Res. 20(3) 372-80.


David Gutmann

Non-invasive technique to detect optic glioma in mouse model of NF1.

Banerjee D., Hegedus B., Gutmann D., and Garbow J. 2007. Detection and measurement of neurofibromatosis-1 mouse optic glioma in vivo. Neuroimage 35:1434-1437.


Harry Joe

Statistical models to analyze NF1 and NF2 genetic and phenotypic data

Baser M et al. 2002. Predictors of the Risk of Mortality in Neurofibromatosis 2. Am J Hum Genet; 71(4): 715-723.


Bruce Korf

Volumetric MRI for measuring growth of plexiform neurofibromas.

Young Poussaint T, Jaramillo D, Chang Y, et al. 2003. Interobserver reproducibility of volumetric MR imaging measurements of plexiform neurofibromas. Am J Radiol 180:419-423.


Margaret Wallace

Method to culture and xenograft human neurofibromin-deficient Schwann cells

Muir D, et al. 2001. Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells. American Journal of Pathology 158(2):501-513.