Ovarian Cancer
Research Highlights/News
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2018
Press Releases:
Research Highlights
- BRCA in Ovarian Cancer: Understanding the Risk and Finding New Means of Treatment
- A Multi-Institutional Approach to Understanding the Pathology of Ovarian Cancer
- A More Reliable Personalized Medicine-Based Approach to Test Ovarian Cancer Drugs
- Cyclin E1 as a Therapeutic Target for High-Grade Serous Ovarian Cancer
- The Impact of the Ovarian Cancer Academy Is Long-Lasting and Far-Reaching
- Investigation of a Novel PET Tracer to Assess PARP Inhibitor Sensitivity in Ovarian Cancer Patients
News:
- Mechanism of Resistance to Novel Targeted Therapy for Ovarian Cancer Identified (external link)
The Wistar Institute, October 15, 2018 - Analgesic Use and Ovarian Cancer Risk (external link)
Oxford Academic, July 19, 2018 - PARP-1 May be Key to Effectiveness of PARP Inhibitors, and Now Researchers Can Image It (external link)
Penn Medicine News, May 3, 2018 - Pushing screening of ovarian and endometrial cancers one step further (external link)
McGill Publications Med e-News, March 30, 2018
2017
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2017 January 30, 2017
Research Highlights
- Evaluation of DNA Repair Function as a Predictor of Response in a Clinical Trial of PARP Inhibitor Monotherapy for Recurrent Ovarian Carcinoma
- Towards Understanding Ovarian Cancer Progression and Chemotherapy Resistance
- Chip-Based Magnetic Imager for Molecular Profiling of Ovarian Cancer Cells
- The Clinical Development Award: Accelerating Ovarian Cancer Research into Clinical Application
- Combination Therapy of JO-c and PEGylated Liposomal Doxorubicin/DoxilTTM in Ovarian Cancer Patients
News:
- Combination immunotherapy holds promise as improved ovarian cancer treatment (external link)
Johns Hopkins University, December 8, 2017 - 3D Cultured Cells Could Drive Precision Therapy for Cancer Treatment (external link)
Comprehensive Cancer Center – Michigan Medicine, November 16, 2017 - Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer (external link)
eLife, November 6, 2017 - Many Pelvic Tumors in Women May Have Common Origin: Fallopian Tubes (external link)
NYU Langone Health, October 31, 2017 - Expert Highlights Immunotherapy Potential in Ovarian Cancer (external link)
OncLive, October 5, 2017 - Bio-inspired approach to RNA delivery (external link)
MIT News, September 25, 2017 - Intrepid DoD Ovarian Cancer Academy Investigator Rugang Zhang Develops Alternative Therapy (external link)
The Wistar Institute, July 28, 2017 - Homologous recombination deficiency analysis predicts PARP inhibitor benefit for ovarian cancer (external link)
Healio - HemOnc Today, February 7, 2017
2016
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2016 January 11, 2016
Research Highlights:
- Providing Hope: Increasing Long-Term Survivorship of Ovarian Cancer Patients
- Genetic Modifiers of Ovarian Cancer Risk in BRCA1 Mutation Carriers
- Optical Imaging Falloposcope for Minimally Invasive Ovarian Cancer Detection
- Ubiquitin-Mediated Protein Degradation Pathways for Ovarian Cancer Treatment
- Repurposing FDA-Approved Drug as a Potential Metastasis Inhibitor for Ovarian Cancer Treatment
- Therapeutic Strategies against Cyclin E1-Amplified Ovarian Cancers
Video Highlights:
News:
- Combination Therapy Improved Chemoresistance in Ovarian Cancer (external link) Wistar, November 21, 2016
2015
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2015 February 19, 2015
Research Highlights:
- Dr. Nita Maihle and Dr. Douglas Levine Lead the Ovarian Cancer Academy
- Tumor Microenvironment Gene Signatures in Ovarian Cancer
- Deciphering the Adaptive Immune Response to Ovarian Cancer
- Classifying Subtypes of High-Grade Serous Ovarian Cancer
- The Ovarian Cancer Academy Expands
News:
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Inhibiting DNA Methylation Causes an Interferon Response in Cancer (external link)
Cell, September 1, 2015 -
Rewriting the Book on Chemo-Resistant Cancers with a DNA Library (external link)
The University of Kansas Cancer Center, June 2, 2015 -
AACR 2015: Olaparib and Investigational PI3K Inhibitor BKM120 Combination Active Against Ovarian and Breast Cancer Subtypes (external link)
The ASCO Post, April 28, 2015 -
New Therapeutic Strategy Discovered for Ovarian (external link)
The Wistar Institute, February 17, 2015 -
Global Deletion of Trp53 Reverts Ovarian Tumor Phenotype of the Germ Cell-Deficient White Spotting Variant (Wv) Mice1 (external link)
Neoplasia, January 30, 2015
2014
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2014 February 24, 2014
Research Highlights:
- Role of Receptor Sialylation in the Ovarian Tumor Cell Phenotype
- Whole Genome Sequencing to Identify Novel Ovarian Cancer Genes
- Rethinking the Spread of Ovarian Cancer
- The Role of Omental Microenvironment in Ovarian Cancer Metastatic Colonization
- Nuclear Factor-Kappa B Activity in the Host-Tumor Microenvironment of Ovarian Cancer
- Seeking to Improve Ovarian Tumor Response to Chemotherapy
News:
-
Oxygen-deprived RNA molecules lead to tumor progression (external link)
MD Anderson Cancer Center, November 4, 2014 -
MD Anderson researchers discover new route for ovarian cancer spread (external link)
MD Anderson Cancer Center, July 17, 2014 -
Researchers at Case Comprehensive Cancer Center Discover Ovarian Cancer Biomarker (external link)
Case Western Reserve University, February 21, 2014
2013
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2013 April 19, 2013
Research Highlights:
- Understanding the Molecular Effects of BRCA mutations
- Ovarian Cancer Consortium for Research and Surveillance - Reducing the Risk
- Genetic Modifiers of Ovarian Cancer Risk in BRCA1 Mutation Carriers
- Identifying Genetic Alterations to Guide Treatment Decisions
- Improving the Understanding of BRCA1/2 Mutation Distributions in Ovarian Cancer
- The Outcomes Consortium Development Award: A Fresh Approach
- FY12 Teal Innovator: Building Better Medicine
- Understanding the Role of the Immune System in the Progression of Ovarian Cancer
- A Clinician Scientist and Advocate, Targeting Resistant Tumor-Founding Cells
News:
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Predicting ovarian cancer by counting tumor-attacking immune cells (external link)
Fred Hutchinson Cancer Research Center, December 10, 2013 -
Ovarian Cancer Tied to Altered Estrogen Metabolism (external link)
University of Nebraska Medical Center, October 24, 2013 -
Versatile microRNAs choke off cancer blood supply, suppress metastasis (external link)
MD Anderson Cancer Center, September 24, 2013 -
Five genetic variations increase risk of ovarian cancer (external link)
Duke Health, April 17, 2013 -
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer (external link)
Nature Communications, April 17, 2013 -
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 (external link)
Nature Communications, April 17, 2013 -
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer (external link)
Nature Genetics, April 17, 2013 -
USC scientists contribute to international research on genetic risks for cancer (external link)
University of Southern California, April 16, 2013 -
Pre-clinical study identifies 'master' proto-oncogene that regulates stress-induced ovarian cancer metastasis (external link)
MD Anderson Cancer Center, February 19, 2013
Video Highlights:
2012
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2012 February 8, 2012
Research Highlights:
- Organizing the Heterogeneity in High-Grade Serous Ovarian Cancer by Mass Cytometry
- Genetic Profiling in the Australian Ovarian Cancer Study
- Premalignant Expression Signature in BRCA-1-mediated Ovarian Cancer
- Understanding Ovarian Cancer Risk Factors
- New Agents for Taxol-Resistant Ovarian Carcinoma
News:
-
Vital samples in short supply as researchers decode chemotherapy resistance in ovarian cancer (external link)
Peter MacCallum Cancer Centre, November 20, 2012 -
Discovery leads to new hope against ovarian cancer (external link)
University of Southern California, October 8, 2012
Video Highlights:
2011
Press Releases:
Research Highlights:
- Ovarian Autoantibodies Predict Ovarian Cancer
- Structural and Functional Analysis of CA125: Potential for Early Diagnosis and Understanding the Immune Evasion Strategies of Epithelial Ovarian Tumors
- Mumps Parotitis and Ovarian Cancer: Modern Significance of an Historic Association
- Targeting Ovarian Cancer
2010
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2010 January 21, 2010
Research Highlights:
- Use of Novel Technologies to Identify and Investigate Molecular Markers for Ovarian Cancer Screening and Prevention - Paving the Way for the Pacific Ovarian Cancer Research Consortium
- Molecular Epidemiology of Ovarian Cancer - Australian Ovarian Cancer Study
- The Biological Basis for Chemoprevention of Ovarian Cancer - The International Ovarian Cancer Association Consortium
News:
-
Ovarian Cancer Advances When Genes Are Silenced (external link)
Published: December 13, 2010 -
Ovarian Cancer Survivor and Advocate: Susan Leighton (external link)
Published: April 26, 2010
2009
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2009 January 20, 2009
Research Highlights:
- Affinity-Based Serum Proteomics for Ovarian Cancer Early Diagnosis
- Resveratrol and Autophagy: Inhibiting Glucose Metabolism to Overcome Chemoresistance
- Polymorphisms, Risk, and the Chemoprevention of Ovarian Cancer
2008
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2008 February 4, 2008
Research Highlights:
- Eliciting Autoimmunity to Ovarian Tumors in Mice by Genetic Disruption of T Cell Tolerance Mechanisms
- Role of Prohibitin in Ovarian Cancer Growth and Apoptotic Mechanisms
- Improving Quality of Life for Women Confronting Ovarian Cancer
- Development and Characterization of Animal Models
2007
Press Releases:
- Department of Defense Ovarian Cancer Research Program Funding Opportunities for Fiscal Year 2007 March 1, 2007
Research Highlights:
- Novel Computational Biology Technologies to Identify Ovarian Cancer Biomarkers that Predict Survival
- New Animal Model to Study Ovarian Cancer
- Ovarian Granulosa Cells Show a New Mechanism for BRCA1-Induced Ovarian Tumorigenesis
- Ovarian Cancer Detection by Elevated Urinary Levels of Bcl2
2006
Press Releases:
Research Highlights:
- A Novel Technology for Early Detection of Serum LPAs in Ovarian Cancer
- Tipping the Balance: KLF6 Isoforms and Ovarian Cancer
- Novel bioinformatics approach to epithelial ovarian cancer marker identification
- New Molecular Technology to Identify Candidate Ovarian Cancer Oncogenes
- Liposome-Based Radiotherapies for the Treatment of Ovarian Cancer
- Training our Nation's Finest Researchers
2005
Research Highlights:
- HOXA9, HOXA10, and HOXA11 as molecular markers and therapeutic targets in ovarian cancer
- Mutant Endostatin: Promising Antiangiogenic Therapeutic Agent for Ovarian Cancer
- Anti-Angiogenic Role of Dendritic Cells in Ovarian Cancer
- Novel Serum Biomarkers for the Detection of Ovarian Cancer
- Squalamine and Cisplatin: Potential Ovarian Cancer Therapeutic Agents
News:
-
Gene Link to Ovarian Cancer Discovered
(external link)
Published: March 28, 2005
2004
Press Releases:
- Ovarian Cancer Research Program for Fiscal Year 2005 September 16, 2004
- Ovarian Cancer Research Program (OCRP) Announces FY2005 (FY05) Funding Mechansims and Schedule August 25, 2004
Research Highlights:
- Development of a Novel Vaccine with Fusions of Dendritic and Ovarian Cancer Cells from Patients
- Blockade Of B7-H1 Improves Myeloid Dendritic Cells Mediated Antitumor Immunity In Ovarian Cancer
- The Use of the Sindbis Vector to Combat Ovarian Cancer
- The Effects of a Vitamin C Derivative on Ovarian Cancer
2003
Press Releases:
- Department of Defense Ovarian Cancer Research Awards July 15, 2003
Research Highlights:
2002
Press Releases:
Research Highlights:
- New Anti-Metastatic and Anti-Angiogenic Compound for Ovarian Cancer
- Development of a Novel Vaccine with Fusions of Dendritic and Ovarian Cancer Cells from Patients
- Regulation of Telomerase Activity in Ovarian Cancer
- Facilitating Decision-Making about Prophylactic Oophorectomy
2001
Press Releases:
Research Highlights:
- Chemoprevention of Ovarian Cancer with Progestins
- Antibody Immunity to Cancer-Related Proteins as a Serologic Marker for Ovarian Cancer
2000
Press Releases:
- Department of Defense Announces Awards Summary for FY99 Ovarian Cancer Research Program October 18, 2000
- FY00 Ovarian Cancer Research Program April 28, 2000
1999
Press Releases:
- FY98 Ovarian Cancer Research Program Awards Summary October 14, 1999
Last updated Monday, October 15, 2018