DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

Vision - To advance mission readiness of U.S. military members affected by cancer and to improve quality of life by decreasing the burden of cancer on Service members, their families, Veterans, and the American public

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Since Fiscal Year 2009, the Peer Reviewed Cancer Research Program (PRCRP) has been charged by U.S. Congress to fund innovative basic, applied, and translational cancer research to support Service members, their families, and the American public. Members of the military are exposed to hazardous environments due to the nature of their service and deployments and, thus, are at risk for the development of many types of cancers. The mission of the PRCRP is to successfully promote high-impact research for cancer prevention, detection, treatment, and survivorship. To accomplish this task, the PRCRP seeks to fund different areas of the research landscape. Funding innovative and translational research the PRCRP offers funding opportunities directed toward the special focus of Service members and potential cancer risks; focusing on the gaps in cancer research with respect to unique situations and military environments. Additionally, the PRCRP addresses growing and developing the future in research through targeted funding opportunities for early career investigators. With a funding program focused on military health and welfare in cancer research, the PRCRP strives to improve the quality of life by decreasing the impact of cancer on Service members, their families and the American public by funding highly relevant and innovative research.

FY21 Peer Reviewed Cancer Research Program Overarching Challenges

The Peer Reviewed Cancer Research Program (PRCRP) has developed a strategy to address multiple issues in cancer research over the spectrum of different cancer topics considered for funding. These Overarching Challenges are critical gaps in cancer research, care, and/or patient outcomes that, if addressed, will advance mission readiness of U.S. military members affected by cancer and will improve quality of life by decreasing the burden of cancer on Service members, their families, Veterans, and the American public.

  • Develop strategies and biomarkers to predict cancer risk, treatment resistance, recurrence, and advanced disease to mitigate risk in target populations.
  • Improve prevention strategies, diagnosis, treatment, and outcomes for patients in underserved or under recognized populations (e.g., military populations, rural populations, communities of color, other minorities, and women).
  • Transform cancer treatment through the identification of novel biomarkers and new targets especially for advanced disease (metastatic and/or recurrence), improve immunotherapy, and eliminate the risks of therapy associated toxicity.
  • Identify and understand the unique and novel features driving cancer presentation to improve outcomes across the spectrum of ages (e.g. children, adolescents, young adults, older adults).
  • Identify and understand the mechanisms behind cancer epigenetics, biological development, etiology, and genetic basis.
  • Develop strategies to improve ease of care/accessibility and to address survivorship issues including quality of life, long-term treatment effects, psychological impact of recurrence, neurocognitive deficits, and overall mental health.
  • Develop and improve minimally invasive methods to detect cancer initiation, recurrence, and progression.
  • Develop open access platform(s) or methods to coordinate and integrate multiple databases, biorepositories, and data sharing interfaces.

Exposure Related Cancer Risks (185kb)



Congressional Appropriations

Congressional Appropriations

Funding Summary

Funding
Summary


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The Peer Reviewed Cancer Research Program (PRCRP) Vision

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Vision

To advance mission readiness of U.S. military members affected by cancer and to improve quality of life by decreasing the burden of cancer on Service members, their families, Veterans, and the American public.

Mission

To successfully promote high-impact research for cancer prevention, detection, treatment, quality of life, and survivorship

Last updated Tuesday, November 16, 2021