Tuberous Sclerosis Complex
Released: January 13, 2016
Defense Health Program
Department of Defense Tuberous Sclerosis Complex Research Program
Funding Opportunities for Fiscal Year 2016 (FY16)
The FY16 Defense Appropriations Act provides $6 million (M) to the Department of Defense Tuberous Sclerosis Complex Research Program (TSCRP) to support innovative, high-impact TSC research. As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency, Research, Development, and Acquisition (DHA RDA) Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
The TSCRP is providing the information in this pre-announcement to allow investigators time to plan and develop applications. FY16 TSCRP Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on the Grants.gov website in March 2016. Pre-application and application deadlines will be available when the Program Announcements are released. This pre-announcement should not be construed as an obligation by the government.
Focus Areas: The goal of the FY16 TSCRP is to encourage innovative research aimed at understanding the pathogenesis, and preventing and treating the manifestations of TSC. Within this context, the FY16 TSCRP encourages applications that address the critical needs of the TSC community in one or more of the following FY16 Focus Areas:
- Understanding phenotypic heterogeneity in TSC
- Gaining a deeper knowledge of TSC signaling pathways and the cellular consequences of TSC deficiency
- Improving TSC disease models
- Developing clinical biomarkers for TSC
- Facilitating therapeutics and clinical trials research
|Award Mechanism||Eligibility||Key Mechanism Elements||Funding|
|Exploration - Hypothesis Development Award||Investigators at all academic levels (or equivalent), including postdoctoral fellows.||
|Idea Development Award||Established Investigators:
Independent investigators with a documented faculty appointment (or equivalent);
Investigators who are early in their faculty appointments or in the process of developing independent research careers.
|Pilot Clinical Trial Award||Must be an independent investigator at or above the level of Assistant Professor (or equivalent).||
|Postdoctoral Training Award||Must have successfully defended a doctoral thesis or possess an M.D. degree.||
|Synergistic Idea Development Award||Each PI must be an independent investigator at or above the level of Assistant Professor (or equivalent).||
A pre-application (letter of intent) is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
Applications must be submitted through the federal government's single-entry portal, Grants.gov. Submission deadlines are not available until the Program Announcements are released. For email notification when Program Announcements are released go to the CDMRP website (https://cdmrp.army.mil) and select Subscribe to Funding Opportunities & Program Communications. For more information about the TSCRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Public Affairs
Last updated Tuesday, January 19, 2016