Released: December 2, 2021
Department of Defense
Congressionally Directed Medical Research Programs (CDMRP)
Epilepsy Research Program
Anticipated Funding Opportunities for Fiscal Year 2022 (FY22)
The FY22 Defense Appropriations Bill has not been signed into law. Although FY22 funds have not been appropriated for the Epilepsy Research Program (ERP), the ERP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY22 funding opportunities. This pre-announcement should not be construed as an obligation by the government.
The FY22 Defense Appropriations Act is anticipated to provide funding for the Epilepsy Research Program (ERP) to understand the mechanisms of post-traumatic epilepsy (PTE) and associated comorbidities to improve quality of life, especially in Service Members, Veterans, and caregivers. The managing agent for the anticipated program announcements/funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).
The ERP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY22 funding opportunities. This pre-announcement should not be construed as an obligation by the government. The FY22 ERP funding opportunity announcements for the following award mechanisms will be posted on the Grants.gov website. Pre-application and application deadlines will be available when the announcements are released.
Applications submitted to the FY22 ERP must address one or more of the following Focus Areas:
- Innovative Research: Tools intended to better inform or improve upon PTE research and care, which may include the following:
- Strategies that will improve seizure detection, characterization, visualization, or diagnosis
- Development of new models or better characterization of existing etiologically relevant models for PTE
- Markers and Mechanisms: Identifying biomarkers or mechanisms of PTE, which may include the following:
- Predictive biomarkers for epileptogenesis (acute and chronic)
- Research into the prevention of epilepsy and/or seizures
- Epidemiology: Epidemiological characterization of PTE following traumatic brain injury (TBI), which may include the following:
- Understanding and improving the quality of life of individuals with PTE, their families, and their caregivers
- Predictors of the development of epilepsy
- Outcomes, including latency to and prevention of epilepsy, comorbidities, and mortality
- Longitudinal Studies: Studies of the evolution of PTE, which may include the following:
- Understanding and improving quality of life of individuals with PTE, their families, and their caregivers
- Treatment and healthcare outcomes research, including quality of care
- Natural history of PTE and prognosis
- Comorbidities (e.g., depression, functional deficits, sleep disorders, major illness)
|Award Mechanism||Eligibility||Key Mechanism Elements||Funding|
|Idea Development Award||Level I: Funding Level I is intended to support early-career investigators ranging from the post-doctoral level to within 3 years of their first independent faculty position (mentor required).
Level II: The Principal Investigator (PI) must be an independent investigator at or above the level of Assistant Professor (or equivalent).
|Intent: To support novel, innovative research to understand the magnitude and underlying mechanisms of PTE.
Applications proposing high-risk, high-reward research are encouraged.
Although preliminary data is not required, evidence demonstrating the ability to execute the chosen model of TBI and/or polytrauma within the applicant’s laboratory or the laboratory of a collaborator is required.
|Research Partnership Award||The PI must be an independent investigator at or above the level of Assistant Professor (or equivalent).||
Intent: To create an avenue for synergistic, collaborative research partnerships between/among investigators to address a research problem or question in a manner that would be unachievable through separate efforts.
Applications must include a Collaboration Plan that outlines the interactions between/among the partners and explains how the expertise of each partner will contribute to the execution of the research project.
|Virtual Post-Traumatic Epilepsy Research Center
Director and Deputy Director: Independent investigators at the level of Associate Professor or above (or equivalent)
Must have a record of PTE publications in peer-reviewed journals
Director and Deputy Director must study different disciplines along the epilepsy care spectrum
Faculty Award: Early-career investigators and investigators new to the PTE field. Must be considered independent researchers at their home institution.
Preliminary data are not required; however, logical reasoning and a sound scientific rationale for the proposed research must be demonstrated
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final funding opportunity announcements that will be available for downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
Submission deadlines are not available until the funding opportunity announcements are released. For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the ERP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Public Affairs
Last updated Tuesday, January 4, 2022